Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma

HIGHLIGHTS

  • who: Haider Tari from the The Institute of Cancer Research, London, UK Queen Mary University of have published the Article: Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma, in the Journal: (JOURNAL) of August/30,/2022
  • what: The authors design a Bayesian inference framework to quantify spatial subclonal interactions between molecular and phenotypically distinct lineages with different patterns of invasion. The authors show how this approach could discriminate genuine interactions where one clone enhanced the invasive phenotype of another from those apparently only due to the complex dynamics of spatially restricted . . .

     

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