HIGHLIGHTS
- who: Yoshiaki Masaki from the Department have published the paper: Quantification of synthetic errors during chemical synthesis of DNA and its suppression by non-canonical nucleosides, in the Journal: Scientific Reports Scientific Reports of 12/05/2022
SUMMARY
Among them, the authors hypothesized that only those side-products, which are recognized by polymerase and cause synthetic errors (substitution, deletion, or insertion), are problematic in genome synthesis. The authors designed a reference sequence to assess the synthetic errors encountered during chemical synthesis (Fig 2). For the analysis of synthetic errors by next-generation sequencers . . .
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