Quantifying epithelial cell proliferation on curved surfaces

HIGHLIGHTS

  • who: November and colleagues from the University of San Diego, United States have published the paper: Quantifying epithelial cell proliferation on curved surfaces, in the Journal: (JOURNAL)
  • what: The authors investigate the effect of Gaussian curvature on epithelial proliferation by growing model MDCK epithelial_cells on toroidal-shaped hydrogels with curvatures on the order of ten cell lengths (sub-millimeters). To quantify how curvature affects proliferation, the authors develop methods to locate cells on surfaces and evaluate the curvature where each cell attaches. Noteworthily, curvature effects on proliferation, the cellular process associated with cell fate and . . .

     

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