Quantitative analysis of genome packaging in recombinant aav vectors by charge detection mass spectrometry

HIGHLIGHTS

• who: Lauren F. Barnes from the DepartmentIndiana University have published the research work: Quantitative analysis of genome packaging in recombinant AAV vectors by charge detection mass spectrometry, in the Journal: (JOURNAL) of 23/Dec/2021
• what: The authors show that the differences between the masses of empty particles and particles with the genome of interest (GOI) are correlated with the expected genome mass. The authors report studies of rAAV8 control vectors containing a variety of target genome lengths produced in insect cells using baculovirus expression. The authors show that CDMS can go beyond simple empty . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.