HIGHLIGHTS
- who: Kristin Johnson from the (UNIVERSITY) have published the Article: Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions, in the Journal: (JOURNAL)
- what: The authors develop an experimental platform and quantitative framework in which pluripotent cells explanted from blastula stage Xenopus embryos can be used to study the transit of these cells to four different lineage states-epidermis, neural progenitor, endoderm and ventral mesoderm-by following changes in the transcriptome at six time points during this seven-hour process. This analysis showed that many known Activin induced transcription factors cluster together . . .
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