Quantitative analysis reveals how egfr activation and downregulation are coupled in normal but not in cancer cells

HIGHLIGHTS

• who: Fabrizio Capuani from the IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello, Milan, Italy, The Microsoft Research-University of Trento Centre for have published the research work: Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 12/08/2015
• what: The authors propose that Cbl binding is the major factor determining the generation of the threshold. In both modules, the authors aimed to use the most standard mathematical representations of the chemical reactions: phosphorylation is described as . . .
  

   

  

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