Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle

HIGHLIGHTS

  • who: Fabrizio Capuani from the Laboratory have published the Article: Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle, in the Journal: Scientific Reports Scientific Reports
  • what: In Fig S6 the authors show how the ATP production increases as a function of β. In Fig 4b, the authors focus on the fluxes through PDHm and LDH, that indicate whether pyruvate is directed towards OXPHOS or fermentation. In Supplementary Fig S1, the authors show that two symmetric cells with unbiased ATP production show identical glucose intake, ATP production, and internal flux distribution. The . . .

     

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