Quantum dot-based screening identifies f3 peptide and reveals cell surface nucleolin as a therapeutic target for rhabdomyosarcoma

HIGHLIGHTS

  • who: Dzhangar Dzhumashev et al. from the Department of Pediatric Hematology and Oncology, Inselspital, Bern University Hospital, Bern, Switzerland have published the article: Quantum Dot-Based Screening Identifies F3 Peptide and Reveals Cell Surface Nucleolin as a Therapeutic Target for Rhabdomyosarcoma, in the Journal: Cancers 2022, 5048 of /2022/
  • what: Based on the results , the authors propose a high and dynamic presence of nucleolin on the cell surface that makes it an attractive target for RMS treatment with proapoptotic ligands such as AS1411 and N6L, or with antibody-drug conjugates (ADC) based on high-affinity . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?