Quinazoline derivatives designed as efflux pump inhibitors: molecular modeling and spectroscopic studies

HIGHLIGHTS

  • who: Ana-Maria Udrea et al. from the Department of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of have published the article: Quinazoline Derivatives Designed as Efflux Pump Inhibitors: Molecular Modeling and Spectroscopic Studies, in the Journal: Molecules 2021, 26, 2374. of /2021/
  • what: The authors evaluated the drug-likeness of quinazoline derivatives BG1189 and BG1190 by applying drug-like rules: Lipinski, Ghose and Veber .
  • how: This Article presents a molecular study of two labelled BG1189 and BG1190 proposed EPIs. In silico ADMET results showed that BG1189 and BG1190 present high . . .

     

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