HIGHLIGHTS
- who: Caitlin R. Francis from the Department of Biological Sciences, University of Denver, Denver, CO, USA have published the research work: Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis, in the Journal: (JOURNAL) of 13/01/2022
- what: The analysis determined that only the Rab35-CA mutant significantly increased both the cells protrusive and retractive capabilities, a finding in line with enhanced migration48 (Fig 7a, b). In a vascular Lifeact-GFP expressing line injected with a sublethal dosage of Rab35A/B single-guide RNA, the authors focused on actin defects. The . . .
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