Rab3gep is the non-redundant guanine nucleotide exchange factor for rab27a in melanocytes*

HIGHLIGHTS

• who: Ana C. Figueiredo from the (UNIVERSITY) have published the paper: Rab3GEP Is the Non-redundant Guanine Nucleotide Exchange Factor for Rab27a in Melanocytes*, in the Journal: (JOURNAL) of August/22,/2008
• what: The authors show that Rab3GEP has guanine nucleotide exchange activity for Rab27a and Rab27b as well as Rab3 proteins, but not for Rabs belonging to other subfamilies.
• how: The authors used a candidate gene approach to identify a nucleotide exchange factor for mammalian Rab27.

SUMMARY

Rab proteins are posttranslationally modified by geranylgeranylation, which is required for . . .

 



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