Rab44 deficiency induces impaired immune responses to nickel allergy

HIGHLIGHTS

  • who: Mayuko Noguromi and collaborators from the Department of Frontier Oral Science, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto, Nagasaki, Japan have published the article: Rab44 Deficiency Induces Impaired Immune Responses to Nickel Allergy, in the Journal: (JOURNAL)
  • what: The authors showed that was upregulated during the early phase of differentiation of M1and M2-type macrophages.

SUMMARY

    Rab GTPases are critical regulators of intracellular membrane trafficking, which is essential for maintaining cellular functions. Distinct from these studies on "small" Rab GTPases, including Rab1-43, immune cell function of the "large . . .

     

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