Rab4a gtpase regulates epithelial-to-mesenchymal transition by modulating rac1 activation

HIGHLIGHTS

• who: Subbulakshmi Karthikeyan from the (UNIVERSITY) have published the article: RAB4A GTPase regulates epithelial-to-mesenchymal transition by modulating RAC1 activation, in the Journal: (JOURNAL)
• what: The studies described above were all performed in MDAMB-231 and MCF7 breast cancer cells. The authors evaluated the crucial involvement of RAB4A in the regulation of EMT through multiple complementary in_vitro and in_vivo approaches.
• how: For this study the authors used MCF7 breast cancer and H1299 non-small cell lung cancer cells that have low intrinsic RAB4A expression and low baseline replating sphere formation ability (Fig . . .
  

   

  

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