Rack1, a new adam12 interacting protein

HIGHLIGHTS

  • who: Katia Bourd-Boittin from the INSERM, IFR140, University of Rennes, Rennes, France have published the research work: RACK1, a New ADAM12 Interacting Protein, in the Journal: (JOURNAL) of SEPTEMBER/19,/2008
  • what: The authors demonstrate the involvement of mediating the PKC-dependent translocation of ADAM12 to membranes of activated hepatic stellate cells. particular treatment of cells with phorbol esters enhances ADAM12 immunostaining the membrane fractions and the co-immunoprecipitation of ternary complexes containing ADAM12 and PKC. This study investigated new partners of ADAM12, a disintegrin and metalloprotease, which has been recently involved in tumor . . .

     

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