Rad51-mediated replication of damaged templates relies on monosumoylated ddk kinase

HIGHLIGHTS

  • who: Chinnu Rose Joseph from the Emato-Oncologia, Via SSofia, Milano, Italy have published the article: Rad51-mediated replication of damaged templates relies on monoSUMOylated DDK kinase, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors aimed to investigate if DDK also contributes to the recombination-mediated DDT branch. Increased DDK expression in human cancers correlates with increased chemoresistance and higher mutation frequencies74. | https://doi.org/10.1038/s41467-022-30215-9 Based on the current results and previously reported analysis of mutation patterns in budding yeast cells, the authors propose that the genomic . . .

     

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