HIGHLIGHTS
- who: Gene Chatman Clark from the Research Centres (HZ), Germany Virginia Commonwealth University, Richmond, VA, United States, Department of Biochemistry have published the paper: Radiation induces ESCRT pathway dependent CD44v3+ extracellular vesicle production stimulating pro-tumor fibroblast activity in breast cancer, in the Journal: (JOURNAL)
- what: The authors demonstrate that ionizing_radiation (IR) stimulates the production of heparan sulfate (HS)+CD44v3+ tEVs (IR-tEVs) from breast cancer cell lines and patients. The authors show that the activity of IR-tEVs is dependent upon vesicular CD44v3 as well as its HS side chains and that their effects . . .
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