HIGHLIGHTS
- who: Colleen S. Curran from the University of Houston, United States have published the research: RAGE pathway activation and function in chronic kidney disease and COVID-19, in the Journal: (JOURNAL)
- future: Work is needed to conclusively establish the role of these three cell surface receptors in SARS-CoV2 pathogenesis and host defense. in the recruitment of immune cells which may include the activity of ICAM-1 RAGE and RAGE ligands. NOTCH activation in podocytes induces injury suggesting that RAGE-induced u03b3-secretase activity may contribute to podocyte injury.
SUMMARY
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