Rapamycin-independent igf2 expression in tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells

HIGHLIGHTS

• who: Blanca E. Himes et al. from the Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of have published the research work: Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells, in the Journal: PLOS ONE | https://doi.org/10.1371/journal.pone [0197105]. May 14, 2018 of /1371/
• what: The authors show here that IGF2 is expressed in TSC2-null mouse embryo fibroblasts (MEFs) and in human LAM cells, but it is insensitive to rapamycin treatment, and thus, targeting its signaling pathway is a potentially novel . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.