Rapamycin limits cd4+ t_cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy

HIGHLIGHTS

• who: Benjamin D. Varco-Merth and collaborators from the Science University, Cleveland Ohio, USA have published the research: Rapamycin limits CD4+ T_cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy, in the Journal: (JOURNAL)
• what: The authors provide for the first time, to the knowledge , a comprehensive assessment of the impact of chronic rapamycin administration on metabolism, gene_expression, and immune cell homeostasis in a clinically relevant NHP model of ART-suppressed SIV infection. While the authors show a low dose of anti-CD3LALA was safe, further studies are required to assess whether . . .
  

   

  

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