HIGHLIGHTS
- who: Jian Xu from the Schoolsen University have published the paper: Rapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA, in the Journal: (JOURNAL) of 11/05/2022
- what: In this study an smRNA encoding a TF was introduced into cells through nongenome-integrating viruses. The authors report for the first time that an smRNAbased differentiation strategy induced highly efficient generation of human OL cells from hiPSC-derived NPCs while OLIG2 smRNA failed to directly reprogram hiPSCs to OLs. The authors propose that exosome-derived infused OPCs may act on . . .
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