Rapid excision of oxidized adenine by human thymine dna glycosylase

HIGHLIGHTS

• who: Hardler W. Servius from the Hardler WServius, Lakshmi S. Pidugu, Matthew E. Sherman, and Alexander C. Drohat* From the Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA Edited by Patrick Sung have published the research work: Rapid excision of oxidized adenine by human thymine DNA glycosylase, in the Journal: (JOURNAL) of October/27,/2022
• what: The authors show that the N140A mutation exerts similarly large effects on oxoA activity with kobs decreases ranging from 11,300-fold (Gu22c5oxoA) to 29,500fold (Tu22c5oxoA) .
• how: The results . . .
  

   

  

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