Rapid macropinocytic transfer of α-synuclein to lysosomes

HIGHLIGHTS

  • who: Armin Bayati from the Montreal Neurological Institute McGill University , Canada have published the research work: Rapid macropinocytic transfer of α-synuclein to lysosomes, in the Journal: (JOURNAL) of July/19,/2022
  • what: Article Limitations of this study While the experiments demonstrate the rapid transport of a-syn PFFs to lysosomes through a unique form of macropinocytosis in a clathrin-independent manner, the authors acknowledge that the study has several limitations. It is important to note that while the authors attempt to examine the internalization of a-syn preformed fibrils, PFFs may not be the true . . .

     

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