Rapid, simple, and effective strategy to produce monoclonal antibodies targeting protein structures using hybridoma technology

HIGHLIGHTS

  • who: Atsumi Sakaguchi from the (UNIVERSITY) have published the paper: Rapid, simple, and effective strategy to produce monoclonal antibodies targeting protein structures using hybridoma technology, in the Journal: (JOURNAL)
  • what: The authors proposed a streptavidin-anchored screening (SAST) as a secondary screening method that retains the advantages of the MIHS method. The authors report the development of a simple two-step screening system that enables the acquisition of mAbs that recognize conformation specific epitopes of the antigens. mAbs can generally be classified into two categories based on their recognition epitope structures . The authors propose three . . .

     

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