Rare variants in lrp4 are associated with mesiodens, root maldevelopment, and oral exostoses in humans

HIGHLIGHTS

  • who: Piranit Nik Kantaputra and colleagues from the Chiang Mai University, Chiang Mai, Thailand have published the paper: Rare Variants in LRP4 Are Associated with Mesiodens, Root Maldevelopment, and Oral Exostoses in Humans, in the Journal: (JOURNAL)
  • what: The authors report the first heterozygous missense variants in LRP4 in patients presenting with mesiodens with or without root maldevelopments and oral exostoses.
  • how: This patient-focused study was conducted in accordance with the Declaration of Helsinki and national guidelines.

SUMMARY

    Tooth formation is a highly orchestrated process involving a well . . .

     

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