Ras gtpase-activating proteins control neuronal circuit development in barrel cortex layer 4

HIGHLIGHTS

  • who: Hidenobu Mizuno from the France (IRCMS), Kumamoto University, Kumamoto, Japan, Graduate School of Medical Sciences have published the Article: Ras GTPase-activating proteins control neuronal circuit development in barrel cortex layer 4, in the Journal: (JOURNAL)
  • what: The authors focused on NF1 and SynGAP for RasGAP KD, because previous studies reported these two molecules were involved in the barrel pattern formation (Barnett et_al, 2006; Lush et_al, 2008). This study showed that the spine number of L4 neurons was not affected by the suppression of RasGAPs.
  • how: For the orientation bias index (OBI . . .

     

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