Rational design of a peptidomimetic inhibitor of gelsolin amyloid aggregation

HIGHLIGHTS

  • who: Michela Bollati et al. from the Institute of Biophysics, National Research Council (IBF-CNR), c/o Department of Biosciences, University of Milano, Via Celoria, Milano, Italy have published the research work: Rational Design of a Peptidomimetic Inhibitor of Gelsolin Amyloid Aggregation, in the Journal: (JOURNAL)
  • what: The u C. elegans as a biosensor is particularly useful for pre-clinical studies aimed at scree rapidly and inexpensively, the activity of new drugs oraimed small_molecules.
  • how: To design novel selective peptidomimetics able to interfere with the formation of amyloidogenic aggregates in tissues of AGel . . .

     

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