Rational peptide design for regulating liquid-liquid phase separation on the basis of residue-residue contact energy

HIGHLIGHTS

• who: Kiyoto Kamagata from the InstitutTohoku University Japan have published the Article: Rational peptide design for regulating liquid-liquid phase separation on the basis of residue-residue contact energy, in the Journal: Scientific Reports Scientific Reports
• what: The authors present a rational design methodology to obtain a peptide that can bind to an IDR using only the IDR sequence information. The authors describe how the newly defined contact energy improves design quality. The former approach aims to increase the solubility of the designed peptide-target protein complex by attaching a soluble tag to the peptides . . .
  

   

  

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