Rational strategies for enhancing mab binding to sars-cov-2 variants through cdr diversification and antibody-escape prediction

HIGHLIGHTS

• who: Masaud Shah and collaborators from the University of Calgary, Canada have published the research work: Rational strategies for enhancing mAb binding to SARS-CoV-2 variants through CDR diversification and antibody-escape prediction, in the Journal: (JOURNAL)
• what: Similar techniques, overlapping with the one propose in the study , have been recently put into practice by AstraZeneca, one of the lead COVID-19 fighting companies .
• how: For CDRs diversifications the authors used overlapping criteria nonetheless to get better insights about the disoriented Epi-Para interface and miss-paired hotspots in RBDMut-mAbs the . . .
  

   

  

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