Rationale and design of the optimize trial: open label multicenter randomized trial comparing standard immunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen in combination with everolimus in de novo renal transplantation in elderly patients

HIGHLIGHTS

  • who: S. E. Boer from the Background: In, more than , % of all newly transplanted kidney transplant recipients in The Netherlands Department of Internal Medicine, Division of Nephrology, University Medical have published the paper: Rationale and design of the OPTIMIZE trial: OPen label multicenter randomized trial comparing standard IMmunosuppression with tacrolimus and mycophenolate mofetil with a low exposure tacrolimus regimen In combination with everolimus in de novo renal transplantation in Elderly patients, in the Journal: (JOURNAL)
  • what: The study showed that the reducedexposure CNI regimen offered comparable efficacy and graft function, with low rates of treated . . .

     

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