HIGHLIGHTS
- who: Ivan de la Rubia from the Laboratory Network, Australia have published the research work: RATTLE: reference-free reconstruction and quantification of transcriptomes from Nanopore sequencing, in the Journal: (JOURNAL)
- what: Using simulated data and experimental data from isoform spike-ins human tissues and cell lines the authors show that RATTLE accurately determines transcript sequences and their abundances and shows good scalability with the number of transcripts. This analysis showed that RATTLE transcripts are longer than RNA-Bloom transcripts for all input sizes and converged to the expected length of the annotation (Additional file 1 . . .
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