Re-examining rotavirus innate immune evasion: potential applications of the reverse genetics system

HIGHLIGHTS

  • who: Avan Antia and collaborators from the Washington University School of Medicine Department of Molecular Microbiology, Washington University School of Medicine, StLouis, Missouri, USA have published the Article: Re-examining rotavirus innate immune evasion: Potential applications of the reverse genetics system, in the Journal: (JOURNAL) of 14/06/2022
  • how: Indicated that type III IFN may play a role in restricting heterologous RRV replication but not homologous EW replication in mice .

SUMMARY

    Sensing of viral dsRNA occurs through cytoplasmic RIG-I-like receptors (RLRs; e_g, RIG-I, MDA5) and/or endosomal . . .

     

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