Reactive astrocytes as drug target in alzheimer’s disease

HIGHLIGHTS

• who: Brhane Teklebrhan Assefa et al. from the DepartmentMekelle University have published the research: Reactive Astrocytes as Drug Target in Alzheimer’s Disease, in the Journal: BioMed Research International of 14/01/2018
• what: The aim of this review is to explore the role of reactive astrocytes in AD.
• future: Research is needed to clarify the overall role of AQP4 in the AD pathophysiological process.

SUMMARY

Histopathological changes such as deposition of extracellular amyloid-? (A?), intracellular neurofibrillary tangles (NFT) of hyperphosphorylated tau, and cortical neuron loss are widely noted . . .

 



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