Real-time visualization of the cellular redistribution of g protein-coupled receptor kinase 2 and ù²-arrestin 2 during homologous desensitization of the substance p receptor*

HIGHLIGHTS

  • who: Larry S. Barak from the (UNIVERSITY) have published the research work: Real-time Visualization of the Cellular Redistribution of G Protein-coupled Receptor Kinase 2 and Ù²-Arrestin 2 during Homologous Desensitization of the Substance P Receptor*, in the Journal: (JOURNAL) of September/14,/1998
  • what: The authors investigate the real-time activation and desensitization of the human SPR in live HEK293 cells using green fluorescent protein conjugates of protein kinase C, GRK2, and b-arrestin 2. The aim of this study was to ascertain the extent and kinetics of GRK and b-arrestin involvement . . .

     

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