Realigning the light signaling network to control dysregulated inflammation

HIGHLIGHTS

  • who: Carl F. Ware and colleagues from the (UNIVERSITY) have published the article: Realigning the LIGHT signaling network to control dysregulated inflammation, in the Journal: (JOURNAL) of 01/03/2023
  • what: The focus of this review centers on the TNFSF-related cytokine, LIGHT (lymphotoxin-like, exhibits inducible expression, and competes with HSV glycoprotein D for herpesvirus entry mediator , a receptor expressed by T lymphocytes), encoded by the TNFSF14 gene.
  • how: Results showed that LIGHT provides a critical signal in the production of lung-resident memory CD8 T_cells following an acute respiratory viral infection . . .

     

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