HIGHLIGHTS
- who: Fajin Li from the (UNIVERSITY) have published the research work: Reanalysis of ribosome profiling datasets reveals a function of rocaglamide A in perturbing the dynamics of translation elongation via eIF4A, in the Journal: (JOURNAL) of 20/05/2022
- what: The authors propose that the identified dual mode of action of RocA should account for its antitumor effect. This study demonstrated the role of RocA in inducing ribosome stalling on the CDS regions in HEK293 cells and a series of other cancerous cells, leading to the accumulation of disomes.
- future: Biochemical studies are . . .
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