Reca and specialized error-prone dna polymerases are not required for mutagenesis and antibiotic resistance induced by fluoroquinolones in pseudomonas aeruginosa

HIGHLIGHTS

• who: Jessica Mercolino et al. from the IRCCS Fondazione Santa Lucia, Rome, Italy have published the research work: RecA and Specialized Error-Prone DNA Polymerases Are Not Required for Mutagenesis and Antibiotic Resistance Induced by Fluoroquinolones in Pseudomonas aeruginosa, in the Journal: Antibiotics 2022, 325 of 28/02/2022
• what: Comparable induction of resistance frequency by ciprofloxacin in all mutants, irrespective of the presence of or the absence RecA (Figure 2b).
• how: This result is apparently in contrast with a previous report that several antibiotics including gentamicin can increase antibiotic resistance frequency in . . .
  

   

  

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