HIGHLIGHTS
SUMMARY
As a common disease with a global prevalence of 10-15%, its diagnosis is made by Rome IV criteria, and this classifies the IBS into four subtypes such as IBS with predominant constipation (IBS-C), IBS with predominant diarrhea (IBS-D), IBS with mixed bowel habits (IBS-M), and IBS unsubtyped or unclassified (IBS-U). In that way, the authors can anticipate the co-occurrence of IBS and FMS in the middle-aged population and help the patients have a better quality of life. Did the review authors provide a satisfactory explanation for and . . .

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