Recent advances in n-o bond cleavage of oximes and hydroxylamines to construct n-heterocycle

HIGHLIGHTS

  • who: Hui-Min Jiang and collaborators from the Nanchang Hangkong University, Nanchang, China have published the research work: Recent Advances in N-O Bond Cleavage of Oximes and Hydroxylamines to Construct N-Heterocycle, in the Journal: Molecules 2023, 28, 1775. of /2023/
  • what: This work shows the possibility of difunctionalization of the enantioselective cross-electrophiles of olefins by heterocyclization, thus providing an opportunity to obtain new chiral scaffolds that represent the first highly enantioselective aza-Heck/crosscoupling sequence, and therefore also establish a new platform for asymmetric aza-Heck and cross-coupling sequences.
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