Recent advances in targeting tumor energy metabolism with tumor acidosis as a biomarker of drug efficacy

HIGHLIGHTS

  • who: Paul J Akhenblit from the University of Arizona, Tucson, AZ, USA have published the article: Recent Advances in Targeting Tumor Energy Metabolism with Tumor Acidosis as a Biomarker of Drug Efficacy, in the Journal: (JOURNAL)
  • what: This review will cover glucose and fatty acid metabolism PI3K/AKT/mTOR HIF-1 and glutamine pathways in energy metabolism and how they are being exploited for treatments and therapies by promising pre-clinical or clinical drugs being developed or investigated.
  • future: Topotecan chemotherapy is used in the clinic to treat small cell lung cancer and . . .

     

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