HIGHLIGHTS
- who: -processing • AIDS/HIV • et al. from the DepartmentUSA M University have published the article: Recent advances in the discovery of small-molecule inhibitors of HIV-1 integrase, in the Journal: (JOURNAL) of 25/07/2018
- what: This review summarizes recent advances up to 2018 in the field of HIV-1 IN inhibitors in connection to major compounds that have made it into clinical trials.
- how: The following two different approaches were explored to target IN and RT enzymes and IN catalytic_site and LEDGF-binding_site to develop dual inhibitors.
SUMMARY
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