Recent advances in the molecular and cellular mechanisms of gp120-mediated neurotoxicity

HIGHLIGHTS

  • who: Valeria Avdoshina and Italo Mocchetti from the Laboratory of Preclinical Neurobiology, Department of Neuroscience, Georgetown University Medical Center have published the research: Recent Advances in the Molecular and Cellular Mechanisms of gp120-Mediated Neurotoxicity, in the Journal: Cells 2022, 11, 1599. of /2022/
  • future: Future research should aim at developing new pharmacological agents that are able to inhibit proBDNF/p75NTR activity and therefore be used against HIV-mediated neuronal toxicity.

SUMMARY

    The failure of cART to reduce HAND can be multifactorial and may include inefficient penetration of drugs through the . . .

     

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