HIGHLIGHTS
- who: Lifang Zhou from the (UNIVERSITY) have published the article: Recent advances in therapeutic CRISPR-Cas9 genome editing: mechanisms and applications, in the Journal: (JOURNAL)
- how: Next clinical data showed that LNP introduced Cas9-sgRNA complex into patients could also reduce their serum TTR levels by up to 87% with low off-target editing.
- future: These tools have provided fantastic new direction for the field of gene and cell therapy. Hopefully in the near future the authors will see further improvements in the efficiency and precise of PE system.
SUMMARY
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