Recent insights into the pathogenesis of acute porphyria attacks and increasing hepatic pbgd as an etiological treatment

HIGHLIGHTS

• who: Daniel Jericu00f3 et al. from the Hepatology Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain have published the research work: Recent Insights into the Pathogenesis of Acute Porphyria Attacks and Increasing Hepatic PBGD as an Etiological Treatment, in the Journal: Life 2022, 1858 of 11/Nov/2022
• what: Based on the PoC obtained in animal models, increasing PBGD levels appears to be a promising strategy for the etiological treatment of AIP, regardless of whether it is achieved by the administration of a recombinant rApoAI-PBGD protein, an rAAV-mediated GT . . .
  

   

  

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