HIGHLIGHTS
- who: Emma G. Norris from the University of Rochester School of Medicine and Dentistry, Rochester, NY , have published the article: Receptor-binding domain of SARS-CoV-2 is a functional u03b1v-integrin agonist, in the Journal: (JOURNAL)
- what: This study provides evidence that cell surface u03b1v-containing integrins can respond functionally spike protein and raises the possibility that S1-mediated dysregulation of ECM dynamics may contribute the pathogenesis and/or post-acute sequelae of SARS-CoV-2 infection. The authors investigated S1-integrin interactions using both primary human small airway epithelial_cells, as well as fibronectinnull . . .
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