Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells

HIGHLIGHTS

  • who: Andrew J. Smith from the SchoolUniversity of London, London EC M BQ, UK have published the article: Receptor tyrosine kinase inhibitors negatively impact on pro-reparative characteristics of human cardiac progenitor cells, in the Journal: Scientific Reports Scientific Reports
  • what: Only a few previous studies have examined RTKI effects on CPCs, with these predominantly focused solely on u00adimatinib37 or u00adtrastuzumab44, while this study shows effects on CPCs from a range of RTKIs.

SUMMARY

    RTKI treatments in_vitro. Drugs were applied by preparing final concentrations in CPC growth ­medium15 and administering to . . .

     

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