HIGHLIGHTS
- who: Sabrina N. Copsel and collaborators from the Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, FL, United States have published the Article: Recipient Tregs: Can They Be Exploited for Successful Hematopoietic Stem Cell Transplant Outcomes?, in the Journal: (JOURNAL)
SUMMARY
Strategies to optimize and exploit their regulatory capacity in different recipient tissues may lead to novel translational strategies for improving allo-HSCT outcomes. some rTregs persisted weeks after transplant, underwent a significant expansion dependent primarily on IL-2, and possessed suppressive function inhibiting T_cell proliferation in_vitro and providing . . .
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