Recombinant bcg expressing ltak63 adjuvant induces superior protection against mycobacterium tuberculosis

HIGHLIGHTS

  • who: Ivan P. Nascimento from the Imunologia, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP), São Paulo, SP, Brazil Laboratório have published the research work: Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis, in the Journal: Scientific Reports Scientific Reports
  • what: The authors demonstrate significant protection against TB challenge in mice using a recombinant BCG expressing the mutated A subunit of LTK63, exploiting the known adjuvant properties of LT.

SUMMARY

    To evaluate if the expression levels of LTAK63 would affect the immune_response . . .

     

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