Reconstituted tad-size chromatin fibers feature heterogeneous nucleosome clusters

HIGHLIGHTS

• who: Nikolay Korolev from the School Technological University have published the paper: Reconstituted TAD-size chromatin fibers feature heterogeneous nucleosome clusters, in the Journal: Scientific Reports Scientific Reports
• what: The authors report that in_vitro reconstitution of nucleosome arrays on native-DNA and u03bb-DNA resulted in heterogeneous nucleosome spacing, which nevertheless form compact single-molecule aggregates consisting of clusters of folded arrays.
• how: A summary of the cluster-cluster ruptures` analysis is presented in Figs 5 and S8.

SUMMARY

To visualize the condensation of TAD-sized chromatin domains, nucleosome . . .

 



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