Reconstructing aspects of human embryogenesis with pluripotent stem_cells

HIGHLIGHTS

• who: Berna Sozen and collaborators from the Department Yale University Cambridge, Cambridge , EG, UK have published the article: Reconstructing aspects of human embryogenesis with pluripotent stem_cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that the resulting structures recapitulate some of the morphological and gene_expression features of embryonic days 3 to day 9/ 10 of natural human embryogenesis with limited developmental potential. The authors aimed to leverage this reported bi-potency of hEPSCs by developing a strategy enabling the authors to reconstitute the spatiotemporal lineage differentiation and self-organisation of human early . . .
  

   

  

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