Recreation of an antigen-driven germinal center in vitro by providing b cells with phagocytic antigen

HIGHLIGHTS

• who: Ana Martu00ednez-Riau00f1o from the The Brabaham Institute University College have published the article: Recreation of an antigen-driven germinal center in vitro by providing B cells with phagocytic antigen, in the Journal: (JOURNAL) of 20/Oct/2022
• what: The analysis showed a mutation frequency within AID hotspots in the Su00b5 region of 5 u00d7 10-4 for bead-bound antigen stimulation which was significantly higher than that of naive B cells and higher than stimulation with soluble antigen (Fig 5c). As an example of the possible uses of the method the authors aimed . . .
  

   

  

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